| Primary Identifier | IPR045223 | Type | Family |
| Short Name | Asc1/RACK1 |
| description | This entry includes Asc1 from yeasts and RACK1 from animals. They are core 40S ribosomal proteins that repress gene expression []. The seven-bladed β-propeller structure of RACK1 is located near the mRNA exit tunnel where it makes contacts with the ribosomal RNA through lysine and arginine residues and neighbouring ribosomal proteins []. RACK1 also serves as a scaffold protein for a wide range of kinases and membrane bound receptors [, ]. It has been shown to regulates axonal growth []and is essential for development in mice, Drosophila melanogaster and Arabidopsis thaliana [, , ]. |
