Primary Identifier | IPR033231 | Type | Family |
Short Name | SECTM1 |
description | Secreted and transmembrane protein 1 (SECTM1), also known as protein K-12, has been identified as a ligand for CD7, an immunoglobulin superfamily molecule with a role in T- and NK-cell activation and cytokine production []. SECTM1 is a potent costimulatory ligand for T cell proliferation and is induced by IFN-gamma [, , ].The human genome contains only one SECTM gene, while the mouse genome contains two (SECTM1A and SECTM1B) []. |