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Protein Domain : Calmodulin regulator protein PCP4

Primary Identifier  IPR033236 Type  Family
Short Name  PCP4
description  PCP4 (purkinje cell protein 4 or PEP-19) is a small calmodulin (CaM)-binding protein that regulates CaM-dependent signalling [, ]. It binds to the C-domain of calmodulin (CaM) via an IQ motif and tunes its Ca(2+) binding properties via an acidic sequence [, , ]. PCP4 is predominantly expressed in the central nervous system, but it is also known to be expressed in other organs. Itmight affect a variety of cellular functions including the control of various neuronal processes [], aldosterone production []and apoptosis [, ].

0 Child Features

0 Parent Features

1 Protein Domain Regions