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Protein Domain : Cleavage stimulation factor subunit 2

Primary Identifier  IPR033105 Type  Family
Short Name  CSTF2
description  Cleavage stimulation factor subunit 2 (CSTF2, also known as CstF-64) is a member of cleavage stimulation factor complex (CSTF), which is necessary for efficient and accurate polyadenylation of most mRNAs. It is necessary for correct histone mRNA 3' end processing as well as maintenance of pluripotency in mouse embryonic stem cells []. In response to epidermal growth factor (EGF), it serves as a major regulator of 3'UTR shortening [].

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9 Protein Domain Regions