Primary Identifier | IPR045148 | Type | Family |
Short Name | TCRG1-like |
description | This entry includes TCRG1/TCRGL from human and related proteins from animals, fungi and plants. TCRG1 (also known as CA150) contains three N-terminal WW domains and six consecutive FF domains. WW and FF domains are versatile modules that mediate protein-protein interactions []. TCRG1 is a transcription elongation factor that interacts with the splicing factor SF1 and with the phosphorylated C-terminal repeat domain (CTD) of RNA polymerase II (RNAPII) through its WW and FF domains, respectively [].This entry also includes Urn1 from budding yeasts and PRP40C from Arabidopsis. They are predicted to be involved in pre-mRNA splicing []. |