| Primary Identifier | IPR033523 | Type | Family |
| Short Name | IRE2 |
| description | Human IRE2 induces translational repression through 28S ribosomal RNA cleavage in response to ER stress []. However, mouse IRE2 does not have this function, instead, it plays a role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis []. |