Primary Identifier | IPR008493 | Type | Domain |
Short Name | Hikeshi-like_dom |
description | This entry represents a domain found in the human protein Hikeshi and its orthologues OPI10 from other eukaryotes. Hikeshi acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress; it acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus []. This entry covers both the dimerisation and jelly roll domains [, ]. |