Primary Identifier | IPR033421 | Type | Domain |
Short Name | Rit1_DUSP-like |
description | Rit1 modifies exclusively the initiator tRNA in position 64 using 5'-phosphoribosyl-1'-pyrophosphate as the modification donor. As the initiator tRNA participates both in the initiation and elongation of translation, the 2'-O-ribosyl phosphate modification discriminates the initiator tRNAs from the elongator tRNAs []. This C-terminal domain shows similarity to dual specificity phosphatases (DUSPs) []. |