| Primary Identifier | IPR008313 | Type | Family |
| Short Name | GH125 |
| description | This family includes proteins from bacteria and fungi. It was originally identified as a protein of unknown function from Schizosaccharomyces pombe, which was isolated from a screen to identify novel genes required for meiosis []. Members of this family have since been characterised from Streptococcus pneumoniae (A0A0H2URZ6) and Clostridium perfringens (Q8XNB2), and represent a new glycoside hydrolase family, also known as GH125. This family is the first characterized metal-independent alpha-mannosidase family []. Proteins in this family have been reported to be strict exo-alpha-1,6-mannosidases that operate via a metal-independent inverting catalytic mechanism []. |
