Primary Identifier | IPR008685 | Type | Family |
Short Name | Centromere_Mis12 |
description | Kinetochores are the chromosomal sites for spindle interaction and play a vital role for chromosome segregation. Fission Saccharomyces cerevisiae kinetochore protein Mis12, is required for correct spindle morphogenesis, determining metaphase spindle length []. Thirty-five to sixty percent extension of metaphase spindle length takes place in Mis12 mutants []. It has been shown that Mis12 might genetically interact with Mal2p []. |