| Primary Identifier | IPR033637 | Type | Family |
| Short Name | ANKS1A |
| description | ANKS1A, also known as Odin, functions as an effector of epidermal derived growth factor receptor (EGFR) recycling [], interacts with 14-3-3 proteins []and restricts platelet-derived growth factor (PDGF)-mediated cell proliferation [].Structurally, it consist of N-terminal ankyrin motifs followed by tandem sterile alpha motif (SAM) domains and a carboxyl phosphotyrosine binding (PTB) domain []. The PTB domain has been shown to be crucial for association with the juxtamembrane domain of ephrin receptor EphA8 [], and the SAM domain is involved in modulating its degradation [], thereby regulating EphA signalling. |
