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Protein Domain : Lipoprotein LenA

Primary Identifier  IPR031024 Type  Family
Short Name  Lipo_LenA_lepto
description  Members of this family are LenA (Leptospira Endostatin-like protein A), found in pathogenic and intermediate species of Leptospira but not in saprophytes. LenA binds plasminogen, laminin, and complement regulator factor H. Behavior during outer membrane solubilisation by low concentrations of Triton X-114 and conservation in all family members of an apparent lipoprotein signal sequence, with invariant Cys residue, strongly suggest that LenA is a lipoprotein. Just outside this family is a full-length homologue found in another spirochete, Turneriella parva DSM 21527 [].

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0 Protein Domain Regions