| Primary Identifier | IPR045658 | Type | Domain |
| Short Name | FRAS1-rel_N |
| description | This entry represents a domain found at the N terminus of FRAS1-related extracellular matrix proteins (also known as Frem related proteins) predominantly in chordates. In humans, the FRAS1-related extracellular matrix protein 1 was reported to be essential for the normal adhesion of the embryonic epidermis []. FRAS1-related extracellular matrix protein 2 is involved in the development of eyelids and the anterior segment of the eyeballs and has been related to cryptophthalmos (a rare congenital disorder characterized by ocular dysplasia with eyelid malformation) [, ]. |
