| Primary Identifier | IPR043032 | Type | Homologous_superfamily |
| Short Name | PvsD/AcsD-like_thumb_helix |
| description | The achromobactin synthetase protein D (AcsD) monomer can be decomposed into three domains that resemble a cupped hand (thumb domain 1, palm domain 2 and fingers domain 3). The Domain 1 (thumb) is a three helix bundle flanked by a four stranded anti-parallel β-sheet that forms the dimer interface. Domain 2 bridges domain 1 to domain 3 and comprises a four-helix bundle sandwiched between a three-stranded antiparallel β-sheet and a two-stranded antiparallel β-sheet. Domain 3 is connected to domain 1 by a 31-residue extended loop (L4), it comprises 182 residues folded in a twisted eight-stranded antiparallel β-sheet interspersed with five α-helices and extended loops [].This superfamily represents the helix bundle of the vibrioferrin amide bond forming protein PvsD, AcsD and related proteins, thumb domain. |
