| Primary Identifier | IPR033527 | Type | Family |
| Short Name | NMI |
| description | Originally identified as an N-Myc-interacting protein, NMI is an interferon-gamma inducible transcription cofactor that is responsible for enhancing IFN-gamma-dependent transcription [, ]. NMI interacts with a variety of transcription factors, including c-Myc, TIP60, some STAT family members, BRCA1, ARF and IRF7 [, , , , , ]. NMI participates in cell cycle control, DNA damage responses and tumorigenesis. It can suppress tumour growth and metastasis by inhibiting NF-kB pathways []and Wnt/beta-catenin signalling []. |
