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Protein Domain : E3 ubiquitin-protein ligase RNF146

Primary Identifier  IPR033509 Type  Family
Short Name  RNF146
description  RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling []. It contains an N-terminal RING domain followed by a WWE domain that binds iso-ADPr. RNF146 is a RING E3 ligase whose activities are regulated by non-covalent ligand binding [].
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3 Protein Domain Regions

Trail: ProteinDomain




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