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Protein Domain : Zymogen granule membrane protein 16

Primary Identifier  IPR033563 Type  Family
Short Name  ZG16
description  ZG16 is a soluble mammalian lectin with a Jacalin-related β-prism-fold that binds both to glycosaminoglycans and mannose []. ZG16 has roles in both the luminal side of the pancreatic zymogen granule membrane (ZGM) and in the mucus layer of the digestive system []. In the ZGM, it functions in the formation of zymogen granules via glycosaminoglycan binding [, , ]. In the digestive system, it seems to be involved in alpha-mannose-related recognition of pathogens [].

0 Child Features

0 Parent Features

2 Protein Domain Regions