| Primary Identifier | IPR031255 | Type | Family |
| Short Name | VPS4 |
| description | There are two mammalian VPS4 isoforms, VPS4A and VPS4B. They belong to the AAA ATPase family. VPS4A is a central regulator for early endosome trafficking [, ]. VSP4 interacts with the ESCRT complex, which directs multiple cellular membrane remodelling events, ranging from the biogenesis of multivesicular bodies and exosomes to the final membrane abscission stage of cytokinesis []. The viral budding via host ESCRT complex can also be regulated by VPS4 []. |
