| Primary Identifier | IPR008900 | Type | Domain |
| Short Name | Zot_N |
| description | This domain is found in bacterial and viral proteins which are very similar to the Zonular occludens toxin (Zot). Zot is elaborated by bacteriophage present in toxigenic strains of Vibrio cholerae. Zot is a single polypeptide chain of 44.8kDa, with the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through mucosal barriers. The Zot biologically active domain was localized towards the C terminus of the protein []. This entry represents the N-terminal domain of Zot. |
