| Primary Identifier | IPR021978 | Type | Family |
| Short Name | DUF3583 |
| description | This domain is found in eukaryotes, and is typically between 302 and 338 amino acids in length. It is found in association with and . Most members are promyelocytic leukemia proteins, and this family lies towards the C terminus. Proteins containing this domain include PML protein from mammals. PML (promyelocytic leukaemia) functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms []. |
