Primary Identifier | IPR043112 | Type | Homologous_superfamily |
Short Name | TIP_C |
description | This superfamily represents the C-terminal of the TBP-interacting proteins (TIPs), which includes several newly discovered transcription factors that could interact with TBP (TATA-box binding protein). This interaction would in turn prevent interaction between TBP and TATA-DNA, required for basal transcription in eukaryotic and archaeal cells. The C-terminal domain comprises three α-helices, six β-strands, and two 3(10)-helices; however, the specific function of this domain is yet to be elucidated []. |