Primary Identifier | IPR006167 | Type | Family |
Short Name | XPF |
description | This entry includes XPF from animals, Rad1 from budding yeasts and Rad16 from fission yeasts. Human XPF is a catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. It is involved in homologous recombination that assists in removing interstrand cross-link []. Budding yeast Rad1 and Rad10 form an endonuclease that specifically degrades single-stranded DNA []. |