| Primary Identifier | IPR033789 | Type | Domain |
| Short Name | Gal11_coact |
| description | GAL11/MED15 (mediator of RNA polymerase II transcription subunit 15) acts in the general regulation of GAL structural genes and is required for full expression for several genes in this pathway, including GALs 1,7, and 10 in Saccharomyces cerevisiae []. GAL11 function is dependent on GCN4 functionality and binds GCN4 in a degenerate manner with multiple orientations found at the GCN4-GAL11 interface [, , ]. This entry represents an activator-binding domain of GAL11. The tertiary structure of this domain has been solved and shows a four-helix fold with a small shallow hydrophobic cleft at its centre into which three Gcn4 aromatic/aliphatic residues are inserted []. |
