| Primary Identifier | IPR045810 | Type | Domain |
| Short Name | eIF3h_C |
| description | This entry represents a C-terminal helical region present in eukaryotic initiation factor 3 chain H.Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome [, ]. It is a non-peptidase homologue in peptidase family M67 (MEROPS identifier M67.971).Results suggest that eIF3h regulates cell growth and viability, and that over-expression of the gene may provide growth advantage to prostate, breast, and liver cancer cells [, , ]. |
