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Protein Domain : PEX8-like, central TPR-like domain

Primary Identifier  IPR060670 Type  Domain
Short Name  PEX8_TPR_mid
description  This entry represents a TPR-like domain found in PEX8 and related eukaryotic peroxisomal membrane proteins. PEX8 proteins are essential components of the machinery required for the import of peroxisomal matrix proteins []. PEX8 binding to the N-terminal region of the PEX5 cargo receptor induces conformational changes in the TPR domains, decreasing their binding affinity to cargo and facilitating the release of PTS1 proteins within the peroxisome []. The specific function of this TPR-like region remains to be determined.

0 Child Features

0 Parent Features

0 Protein Domain Regions