| Primary Identifier | IPR060699 | Type | Domain |
| Short Name | RBM48_helix |
| description | This entry represents the single helix domain of RNA-binding protein 48 (RBM48), located adjacent to the N-terminal RRM domain. RBM48 is a component of the minor spliceosome involved in the splicing of U12-type introns in pre-mRNAs []. The protein interacts with ARMC7 and PRPF8 within the spliceosomal complex. RBM48 contains an RRM domain at its N-terminal region and shows alternative splicing. The protein belongs to the RBM48 family and is found across vertebrates.In the structure of human minor spliceosome (), this domain is involved in interaction with the ARMC7 []. The RBM48-ARMC7 complex binds the ��-monomethyl phosphate cap of the guanine nucleotide at the 5' end of U6atac snRNA through extensive interactions. |
