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Protein Domain : IFT122, second beta-propeller domain

Primary Identifier  IPR056152 Type  Domain
Short Name  Beta-prop_IFT122_2nd
description  This entry represents the second ��-propeller of IFT122, which is a crucial subunit for IFT-A integrity [].Intraflagellar transport protein 122 homolog (IFT122) is one of the core components (together with WDR19/IFT144 and IFT140) of the IFT-A complex which is required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), being involved in cilia function and/or assembly [, ]. IFT-A polymerises interacts with IFT-B, and uses an array of ��-propeller and TPR domains to create 'carriages' of the IFT train that engage TULP adaptor proteins [].

0 Child Features

0 Parent Features

2 Protein Domain Regions