| Primary Identifier | IPR056154 | Type | Domain |
| Short Name | Beta-prop_IFT140_1st |
| description | This entry represents the first ��-propeller of IFT140.IFT140 is one of the core components (together with WDR19/IFT144 and IFT122) of the IFT-A complex which is required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), being involved in cilia function and/or assembly [, ]. IFT-A polymerises interacts with IFT-B, and uses an array of ��-propeller and TPR domains to create 'carriages' of the IFT train that engage TULP adaptor proteins []. The ��-propeller domains of IFT140 contact the ��-propeller domains of IFT121 from the adjacent complex []. |
