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Protein Domain : Prolow-density lipoprotein receptor-related protein 1-like, beta-propeller domain

Primary Identifier  IPR032485 Type  Domain
Short Name  LRP1-like_beta_prop
description  This is a ��-propeller domain found in Prolow-density lipoprotein receptor-related protein 1 (LRP1) from human, an endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells [, ]. LRP1 is involved in cellular lipid homeostasis and in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. It acts as an LRPAP1 alpha-2-macroglobulin receptor [, ].

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0 Protein Domain Regions