| Primary Identifier | IPR056803 | Type | Domain |
| Short Name | ATR-like_N-HEAT |
| description | This region of HEAT repeats is found in human Serine/threonine-protein kinase ATR and similar proteins from vertebrates. This entry represents the N-HEAT region.ATR acts as a DNA damage sensor and is associated with severe disorders such as Seckel syndrome 1. This protein is organised into a large N-terminal ��-solenoid containing HEAT repeats, a FAT (FRAP, ATM, TRRAP) domain (), a kinase domain (), and a C-terminal short segment referred to as FATC (). N-terminal part has two continuous HEAT repeat regions, the N-HEAT and the M-HEAT. The FAT domain contains TPR (tetratricopeptide) repeats followed by a HEAT repeat domain []. |
