| Primary Identifier | IPR057564 | Type | Domain |
| Short Name | HEAT_ATR |
| description | This region of HEAT repeats is found towards the C-terminal of the FAT domain in human Serine/threonine-protein kinase ATR and similar eukaryotic proteins.ATR acts as a DNA damage sensor and is associated with severe disorders such as Seckel syndrome 1. This protein is organised into a large N-terminal ��-solenoid containing HEAT repeats, a FAT (FRAP, ATM, TRRAP) domain (), a kinase domain (), and a C-terminal short segment referred to as FATC (). N-terminal part has two continuous HEAT repeat regions, the N-HEAT and the M-HEAT. The FAT domain contains TPR (tetratricopeptide) repeats followed by a HEAT repeat domain []. |
