| Primary Identifier | IPR057855 | Type | Domain |
| Short Name | Beta-prop_WDR19_1st |
| description | This entry represents the first ��-propeller of WRD19 (also known as IFT144) from animals and the orthologue from C.elegans DYF2. This domain is also found in the WD repeat-containing protein 39-A/B from Salmo salar.WDR19 is a core component of the IFT complex A (IFT-A, together with IFT140 and IFT122), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), being involved in cilia function and/or assembly [, ]. IFT-A polymerises interacts with IFT-B, and uses an array of ��-propeller and TPR domains to create 'carriages' of the IFT train that engage TULP adaptor proteins []. |
