| Primary Identifier | MGI:2675672 | Allele Type | Spontaneous |
| Gene | Noxo1 | Inheritance Mode | Recessive |
| Strain of Origin | SJL.Cg-Thy1<a> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The molecular lesion in the head slant mouse is a single insertion of a deoxyadenosine residue into exon 1, 28 nucleotides from the start codon. This frameshift mutation is predicted to result in a truncation of the encoded protein after the 34th amino acid. In addition, the transgenic expression of the wild-type gene rescued the defects in the homozygous mutant mouse. |
