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Allele : Tie1<tm1.1(icre/Esr1*)Hrr> tyrosine kinase with immunoglobulin-like and EGF-like domains 1; targeted mutation 1.1, Hans-Reimer Rodewald
Primary Identifier  MGI:6279996 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Tie1
Transmission  Germline Strain of Origin  Not Specified
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A tamoxifen-inducible codon-improved Cre recombinase (iCre) flanked by two mutated estrogen receptor sites (MeriCreMer) was inserted into the first exon of the Tie1 locus in embryonic stem cells to express the fusion protein MeriCreMer under the control of the endogenous Tie1 promoter. The FRT-flanked Neo cassette was subsequently removed by crossing mice with FLP deleter mice.
  • mutations:
  • Insertion
  • synonyms:
  • Tie1<MiCreM>,
  • Tie1<MiCreM>,
  • Tie1<tm1.1(icre/Esr1*)Aug>,
  • Tie1<tm1.1(icre/Esr1*)Aug>,
  • Tie1<MiCreM deltaNeo>,
  • Tie1<MiCreM deltaNeo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Carried By

1 Driven By

Trail: Allele

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Trail: Allele




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