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Allele : Kit<W-2Btlr> KIT proto-oncogene receptor tyrosine kinase; viable dominant spotting 2 Bruce Beutler

Primary Identifier  MGI:3779022 Allele Type  Chemically induced (ENU)
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  The Pretty2 mutation corresponds to an A-to-T transversion at nucleotide position 2388 of the gene (Genbank: NM_021099), in the 17th of 21 total exons, resulting in replacement of isoleucine by phenylalanine at amino acid position 787 (I787F) in the C-lobe of the protein, immediately preceding the kinase catalytic loop.
  • mutations:
  • Single point mutation
  • synonyms:
  • Pretty2,
  • Kit<787F>,
  • Kit<m2Btlr>,
  • Pretty2,
  • Kit<787F>,
  • Kit<m2Btlr>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele