Primary Identifier | MGI:3779022 | Allele Type | Chemically induced (ENU) |
Gene | Kit | Inheritance Mode | Semidominant |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | Beutler Mutagenetix |
molecularNote | The Pretty2 mutation corresponds to an A-to-T transversion at nucleotide position 2388 of the gene (Genbank: NM_021099), in the 17th of 21 total exons, resulting in replacement of isoleucine by phenylalanine at amino acid position 787 (I787F) in the C-lobe of the protein, immediately preceding the kinase catalytic loop. |