Primary Identifier | MGI:1861123 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Med1 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exons 12-14 were disrupted with a PGK-neo cassette via homologous recombination resulting in the loss of 2 LXXLL motifs. Northern and Western blot analysis of fibroblasts from homozygous mutant embryos showed absence of gene transcript and protein product. |