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Allele : Med1<tm1Jkr> mediator complex subunit 1; targeted mutation 1, Janardan K Reddy

Primary Identifier  MGI:1861123 Allele Type  Targeted
Attribute String  Null/knockout Gene  Med1
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129P2/OlaHsd-Hprt1<b-m3> Is Recombinase  false
Is Wild Type  false
molecularNote  Exons 12-14 were disrupted with a PGK-neo cassette via homologous recombination resulting in the loss of 2 LXXLL motifs. Northern and Western blot analysis of fibroblasts from homozygous mutant embryos showed absence of gene transcript and protein product.
  • mutations:
  • Insertion
  • synonyms:
  • PBP<->,
  • PBP<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele