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Allele : Card9<tm1Tks> caspase recruitment domain family, member 9; targeted mutation 1, Takashi Saito

Primary Identifier	MGI:3715521	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Card9
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 2, including the ATG start codon and the CARD-encoding region, was replaced with a neomycin resistance cassette. Absence of protein was confirmed by immunoblot analysis.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Card9<->,
Card9<->

earliestPublication:
Hara H, et al. (2007) The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors. Nat Immunol 8(6):619-29

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

26 Publication categories

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