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Allele : Bdnf<tm1Jae> brain derived neurotrophic factor; targeted mutation 1, Rudolf Jaenisch

Primary Identifier  MGI:1857136 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bdnf
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129S4/SvJae Is Recombinase  false
Is Wild Type  false
molecularNote  A part of exon 5 of the gene was deleted and replaced by a neomycin cassette. This deletion left 49 and 30 amino acids in the N and C termini, respectively. Northern blot analysis on RNA derived from cerebral cortex showed that no detectable transcript is expressed from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • BDNF<->,
  • BDNF-KO,
  • BDNF-KO,
  • BDNF<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

152 Publication categories

Trail: Allele