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Allele : Pcsk9<tm1Jdh> proprotein convertase subtilisin/kexin type 9; targeted mutation 1, Jay D Horton

Primary Identifier  MGI:3577021 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pcsk9
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a neomycin resistance gene was inserted to replace the 3' half of exon 2 through exon 4. Northern blot of mutant livers confirmed absence of transcript. Immunoblot of livers further confirmed absence of protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pcsk9<->,
  • Pcsk9<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

38 Publication categories

Trail: Allele