Primary Identifier | MGI:7435644 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Dzip1 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology targeting exon 2 generated a 31 bp deletion, c.102_132del, resulting in a frameshift mutation that is predicted to cause a premature translational termination (p.Ala35Serfs*13). Western blot analysis confirmed absence of protein in homozygous whole testis lysates. |