|  Help  |  About  |  Contact Us

Allele : H2-Ab1<g7-em1Mvw> histocompatibility 2, class II antigen A, beta 1; endonuclease-mediated mutation 1, Michael Wiles
Primary Identifier  MGI:6156109 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  H2-Ab1
Inheritance Mode  Not Specified Strain of Origin  NOD.Cg-Prkdc<scid> H2-K1<b-tm1Bpe> H2-D1<b-tm1Bpe> Il2rg<tm1Wjl>/Sz
Is Recombinase  false Is Wild Type  false
molecularNote  This TALEN-mediated null mutation has a 61 bp deletion in exon 2, Chr 17: :34264928-34264988 (GRCm38), followed by 39 bp of retained endogenous sequence, then a 507 bp deletion, Chr 17: 34265028-34265534, with a 7 bp insertion (CCGTCAC) in its place, the impact of which is a disruption of most of exon 2. Flow cytometric analysis confirmed this to be a null allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • H2-Ab1<em1Mvw>,
  • IA<null>,
  • IA<null>,
  • H2-Ab1<em1Mvw>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom