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Allele : Sp3<tm2.1Sus> trans-acting transcription factor 3; targeted mutation 2.1, Guntram Suske
Primary Identifier  MGI:4887404 Allele Type  Targeted
Gene  Sp3 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was replaced with one in which nucleotide substitutions result in the amino acid substitution of glutamic acid for aspartic acid at position 553 (D553E). This allele is expected to produce a SUMOylation-deficient protein. A floxed lacZ-neo cassette inserted downstream of the modified exon 5 was removed by cre-mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Sp3<ki>,
  • Sp3<ki>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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