Primary Identifier | MGI:2447704 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pmp22 |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by insertion of a neo-derived cassette into exon 2 at amino acid 8. Absence of gene expression was confirmed by Western blot analysis of sciatic nerve homogenates from ten-week old homozygous mutant animals using antibodies directed against residues 117-132 of the protein. |