|  Help  |  About  |  Contact Us

Allele : Bhmt<tm1.2Zei> betaine-homocysteine methyltransferase; targeted mutation 1.2, Steven Zeisel

Primary Identifier  MGI:5297083 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bhmt
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  One loxAPA site was inserted in intron 5 240 bp upstream of exon 6 and an FRT flanked MC1-neomycin cassette followed by a second loxP site was placed 330 bp from exon 7. The neomycin selection cassette was excised by crossing to Tg(ACTFLPe)9205Dym mice. Exons 6 and 7, containing the essential zinc binding domain, were then removed by crossing to Tg(EIIa-cre)C5379Lmgd mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele