Primary Identifier | MGI:5302080 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dpp6 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2 and the neo cassette. Immunohistochemistry confirmed the absence of protein expression in the brain. |