| First Author | Lewis SE | Year | 1978 |
| Journal | J Reprod Fertil | Volume | 53 |
| Issue | 2 | Pages | 197-202 |
| PubMed ID | 690964 | Mgi Jnum | J:6034 |
| Mgi Id | MGI:54511 | Doi | 10.1530/jrf.0.0530197 |
| Citation | Lewis SE, et al. (1978) Fertility studies of complementing genotypes at the albino locus of the mouse. J Reprod Fertil 53(2):197-202 |
| abstractText | Mice doubly heterozygous for two radiation-induced lethal alleles at the albino locus (C3H and C6H) show partial complementation: they are viable but runted and sterile. In C3H/C6H females oogenesis and mating are normal, but nearly all of their fetuses, even when genotypically normal (+/C3H or +/C6H), fail to survive beyond midgestation. Abnormalities of spermatogenesis, i.e. morphological defects in head condensation and a deficiency in numbers of maturing spermatids, are histologically detectable in the testes of C3H/C6H males. Spermatozoa from the vasa deferentia of such males are predominantly nonviable, immotile, and grossly abnormal in morphology. |
