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Allele : Tert<tm1Yjc> telomerase reverse transcriptase; targeted mutation 1, Y Jeffrey Chiang

Primary Identifier  MGI:3052737 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tert
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A GFPneo was inserted into the 5' UTR of exon 1. Southern blot and PCR confirmed recombination in mutant mice. RT-PCR showed a lack of transcript in mutants and a telomerase repeat amplification (TRAP) assay indicated there was no telomerase activity in testis cell extracts from mutants.
  • mutations:
  • Insertion
  • synonyms:
  • TERT<->,
  • mTERT<->,
  • TERT<->,
  • mTERT<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

21 Publication categories

Trail: Allele