Primary Identifier | MGI:3052737 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tert |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A GFPneo was inserted into the 5' UTR of exon 1. Southern blot and PCR confirmed recombination in mutant mice. RT-PCR showed a lack of transcript in mutants and a telomerase repeat amplification (TRAP) assay indicated there was no telomerase activity in testis cell extracts from mutants. |