Primary Identifier | MGI:7341848 | Allele Type | Endonuclease-mediated |
Gene | Kcnc3 | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A G-to-T missense mutation (chr7:44,595,588, mm10) is introduced to exon 2 using CRISPR/cas9 methodologies and a gRNA targeting ACGCAGCCCCACGAAGTGACGG. The mutation resulted in a glycine-to-valine mutation (p.G434V). |