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Allele : Mre11a<tm1.1Rchd> MRE11A homolog A, double strand break repair nuclease; targeted mutation 1.1, Stephane Richard
Primary Identifier  MGI:5320419 Allele Type  Targeted
Gene  Mre11a Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Nine arginine residues in exon 14 were replaced with lysine (R->K) in this knock-in strain. The targeting cassette carried a loxP-flanked R->K segment, FRT site, PGK-neomycin cassette, loxP site, and FRT site. Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • MRE11<RK>,
  • MRE11<RK>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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