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Allele : Tg(LPV-TAg)#Tvd transgene insertion #, Terry Van Dyke
Primary Identifier  MGI:3531492 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(LPV-TAg)#Tvd
Strain of Origin  (C57BL/6J X DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene consists of a lymphotrophic papovavirus (LPV) enhancer/early promoter and an SV40 T antigen sequence which cannot express the small t antigen due to a deletion of the splice donor site. The Large T antigen retains Trp53 and Rb1/p107 binding function. Regulatory sequences direct expression of the transgene in B- and T- lymphocytes and choroid plexus epithelium.
  • mutations:
  • Insertion
  • synonyms:
  • LPV-TAg,
  • LPV-TAg,
  • LST,
  • LST
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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